Appleford-on-Thames is a village and civil parish on the south bank of the River Thames about 2 miles (3 km) north of Didcot, Oxfordshire. It was part of Berkshire until the 1974 local government boundary changes. The 2011 Census recorded the parish's population as 350. == Archaeology == Evidence of Romano-British settlement has been found in a field south of the parish church plus ceramics and human burials of the same period at Manor Farm. In 1968 the Appleford Hoard of 4th-century Roman artefacts was found.

Appleford Railway Bridge carries the Cherwell Valley Line from Didcot to Oxford across the River Thames near the village of Appleford-on-Thames, Oxfordshire, England. It crosses the Thames on the reach between Clifton Lock and Culham Lock. Originally, a timber bridge was built at the approximate location of the present bridge; by December 1843, it was reportedly under construction, and was completed during the following year. By the 1850s, it has been replaced by a more substantial bridge principally composed of wrought iron so that heavier trains could be run along the line. A third bridge was completed in 1927, which was built out of steel; it is this structure that is presently used as of the 2010s.

Appleford railway station serves the village of Appleford-on-Thames in Oxfordshire, England, as well as nearby settlements such as Sutton Courtenay. It is on the Cherwell Valley Line between Didcot Parkway and Banbury, 55 miles 16 chains (88.8 km) measured from London Paddington. The station and all trains serving it are operated by Great Western Railway. == Layout == The station entrance is on a humpback bridge and passengers must descend steep steps to the platforms. Platform 1 is for Down trains towards Oxford, and Platform 2 is for Up trains towards London Paddington.

Culham railway station serves the village of Culham in Oxfordshire, England. It is on the Cherwell Valley Line between Didcot Parkway and Banbury, 56 miles 17 chains (90.5 km) from London Paddington. It is served by local train services provided by Great Western Railway. The station is just off the A415 road, between the villages of Culham and Clifton Hampden. It is close to Culham Science Centre, an 80-hectare (200-acre) scientific research site housing two nuclear fusion experiments: JET and MAST. The Science Centre was built on the site of RNAS Culham (HMS Hornbill), a World War II airfield.

The East Hendred Brook is a small tributary of the River Thames which starts on the springline at the base of the Berkshire Downs, and joins the Thames between Abingdon and Wallingford.